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Study 3


Case Study: Treating Bleeding Gums & Halitosis


Kayhan Civelek DDS

A patient referred to our office with a chief complaint of bleeding gums and halitosis. Initial examination included; clinical evaluation of intraoral soft tissue including gums tongue and the buccal mucosa. Hard tissue examination was performed via digital x rays, and initial DNA analysis was done to determine the type of microorganism that was present in the mouth specially in the in sulcus/periodontal pocket. Further more periodontal evaluation with full mouth probing was performed by a periodontist.

The result of initial evaluation revealed generalized active periodontitis with an average of 20-25% attachment loss.

The initial treatment consist of improving home care and scaling, root planing. A four-week post evaluation revealed no change in the clinical signs of active inflammation. Bleeding on Probing (BOP), the color, consistency and the texture of soft tissue did not show any improvement. The result of post scaling DNA did not show major shift in the pathologic microbiota.

New studies that were published in JADA and JAMA explain how nutrition plays a major role improving immune response to infection. Therefore, we decided to improve the patient's overall diet with a new supplement that is called OSTEOPRO. The patient was asked to mix one cup of powder with a glass of water and drink it twice a day.

After six weeks the patient was evaluated to see any possible changes of the intraoral soft tissue. The color of the gingivae was changed from magenta red to rose pink; it was more firm and resilient. Further- more the BOP sites were reduced by 80%. Surgical treatment was performed with bone graft and he was gained the lost attachment; 6 months after the initial treatment these results are stable. He has supplemented his diet with OSTEOPRO ever since.


Fig. 1 - Before. There is a localized attachment loss resulting from a fistula between the 1st and 2nd. implants to the right.


Fig. 2 - After 3 months on OsteoPro. Notice the greater density of bone where the fistula had been.


Case Study: Treating Bleeding Gums & Halitosis

Since the result of this single case in our office we have decided to perform double-blinded study in a real world private office setting. This study was designed to determine the effect of OSTEOPRO at the post initial and post surgical phase of the treatment. 10 patients in each group with similar periodontal conditions were selected. One of the group received OSTEOPRO the other placebo neither the doctors nor the patient knew which group was active, which was a placebo group. Initial evaluation included pocket measurements, clinical evaluation of gingival such as color consistency, texture and BOP. Initial treatment included scaling, root planning and improving home care and supplements. Post initial evaluation 78% improvement in the clinical parameters of OSTEOPRO group where placebo group revealed only 31% improvement.

Second Phase

Second phase of the treatment was continuation of the first phase to the surgical treatment. Similar results were found the active group demonstrated 72% increases in the attachment level where placebo group only 26%.




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The information presented here is for educational purposes only. The FDA has not evaluated these statements. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your health care professional before starting any nutritional supplement regime.